Title Polycomb Genes , miRNA , and Their Deregulation in B - cell Malignancies Gang
نویسندگان
چکیده
Correspondence: Dr. Jianguo Tao, Departments of Hematopathology and Laboratory Medicine, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA; email: [email protected] tel: 813-745-3885 fax: 813-745-1708 Co-correspondence: Dr. G. Greg Wang, Lineberger Comprehensive Cancer Center,University of North Carolina at Chapel Hill, 450 West Dr, CB 7295,Chapel Hill, NC 27599; e-mail: [email protected]: 919-966-5952 fax: 919-966-9673 Blood First Edition Paper, prepublished online January 7, 2015; DOI 10.1182/blood-2014-10-606822
منابع مشابه
Polycomb genes, miRNA, and their deregulation in B-cell malignancies.
Posttranslational modifications of histone proteins represent a fundamental means to define distinctive epigenetic states and regulate gene expression during development and differentiation. Aberrations in various chromatin-modulation pathways are commonly used by tumors to initiate and maintain oncogenesis, including lymphomagenesis. Recently, increasing evidence has demonstrated that polycomb...
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MicroRNAs (miRNAs) are small non-coding RNAs that play important post-transcriptional regulatory roles in a wide range of biological processes. They are fundamental to the normal development of cells, and evidence suggests that the deregulation of specific miRNAs is involved in malignant transformation due to their function as oncogenes or tumor suppressors. We know that miRNAs are involved in ...
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تاریخ انتشار 2015